Ago2	Argonaute-2
AKT	Protein kinase B
BSA	Buried Surface Area
CHARMM-GUI	Chemistry at Harvard Macromolecular Mechanics–Graphical User Interface
DCCM	Dynamic cross-correlation matrix
DSSP	Define Secondary Structure of Proteins
EMM	Molecular mechanics energy
FEL	Free energy landscape
FOXO3a	Forkhead box O3a
GROMACS	GROningen MAchine for Chemical Simulations
HADDOCK	High Ambiguity Driven Biomolecular DOCKing
MD	Molecular dynamics
miRNA	Micro-ribonucleic acid
DMA	Dimethylated arginine
MMPBSA	Molecular mechanics Poisson-Boltzmann surface area
MT	Mutant
NF-κB	Nuclear factor kappa B
PC	Principal component
PDB	Protein Data Bank
PI3K	Phosphatidylinositol 3-kinase
PTEN	Phosphatase and tensin homolog
Rg	Radius of gyration
RISC	RNA-induced silencing complex
RMSD	Root mean square deviation
RMSF	Root mean square fluctuation
SASA	Solvent accessible surface area
SND1	Staphylococcal nuclease domain-containing protein 1
WT	Wild type
ΔG	Gibbs free energy change