| ADAP | Adhesion and degranulation-promoting adapter protein |
| AIM2 | Absent in melanoma 2 |
| ARIH1 | Ariadne RBR E3 ubiquitin protein ligase 1 |
| ASFV | African swine fever virus |
| Aza | 5-azacytidine |
| BMM | Bone marrow-derived macrophage |
| CCHFV | Crimean–Congo hemorrhagic fever virus |
| cGAS | Cyclic GMP-AMP synthase |
| CMV | Cytomegalovirus |
| DAMP | Damage-associated molecular pattern |
| DDX41 | DEAD-box helicase 41 |
| DSB | Double-stranded break |
| dsDNA | Double-stranded DNA |
| dsRNA | Double-stranded RNA |
| DUB | Deubiquitinating enzyme |
| EMCV | Encephalomyocarditis virus |
| ER | Endoplasmic reticulum |
| ERV | Endogenous retrovirus |
| ESCRT | Endosomal sorting complex required for transport |
| FMDV | Foot-and-mouth disease virus |
| HDAC6 | Histone deacetylase 6 |
| HEK293 | Human embryonic kidney cell line 293 |
| HepG2 | Hepatic glycoprotein 2/hepatocellular carcinoma cell line 2 |
| HERC5 | HECT and RLD domain-containing E3 ubiquitin protein ligase 5 |
| Herc6 | HECT and RLD domain-containing E3 ubiquitin protein ligase 6 |
| HIV-1 | Human immunodeficiency virus type 1 |
| HSV-1 | Herpes simplex virus type 1 |
| IAV | Influenza A virus |
| IBV | Influenza B virus |
| iBMM | Immortalized bone marrow-derived macrophage |
| IFI16 | Interferon gamma-inducible protein 16 |
| IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1 |
| IFN | Interferon |
| IFN-I | Type I interferon |
| IFN-II | Type II interferon |
| IFN-α | Interferon-alpha |
| IFN-β | Interferon-beta |
| IFN-γ | Interferon-gamma |
| IFN-ε | Interferon-epsilon |
| IFN-κ | Interferon-kappa |
| IFN-ω | Interferon-omega |
| IFNAR | Interferon-alpha/beta receptor |
| IFNAR1/2 | Interferon-alpha/beta receptor subunits 1 and 2 |
| IKKε | IκB kinase-epsilon |
| IL-6/IL-10/IL-12/IL-18 | Interleukin 6/10/12/18 |
| IL-18Rα | Interleukin 18 receptor alpha |
| IP | Immunoprecipitation |
| IPS-1 | Interferon promoter-stimulator 1 |
| IRF3/IRF7/IRF9 | Interferon regulatory factor 3/7/9 |
| ISG | Interferon-stimulated gene |
| ISG15 | Interferon-stimulated gene 15 |
| ISGF3 | Interferon-stimulated gene factor 3 |
| ISRE | Interferon-stimulated response element |
| JAK1 | Janus kinase 1 |
| LFA-1 | Lymphocyte function-associated antigen 1 |
| LGP2 | Laboratory of genetics and physiology 2 |
| LRRC25 | Leucine-rich repeat containing protein 25 |
| MAVS | Mitochondrial antiviral-signaling protein |
| MDA5 | Melanoma differentiation-associated protein 5 |
| MEF | Mouse embryonic fibroblast |
| MERS-CoV | Middle East respiratory syndrome coronavirus |
| MPXV | Monkeypox virus |
| MS | Mass spectrometry |
| MX1/MxA | Myxovirus resistance 1/Myxovirus resistance protein A |
| MOV10 | Moloney leukemia virus 10 |
| Nbs1 | Nijmegen breakage syndrome 1 |
| NEMO | NF-κB essential modulator |
| NF-κB | Nuclear factor kappa-light-chain-enhancer of activated B cells |
| NK | Natural killer |
| NLRP3 | NLR family pyrin domain-containing 3 |
| NSP | Non-structural protein |
| OTU | Ovarian tumor |
| PAM | Porcine alveolar macrophage |
| PAMP | Pathogen-associated molecular pattern |
| PLpro | Papain-like protease |
| poly(I:C) | Polyinosinic–polycytidilic acid |
| PRR | Pattern recognition receptor |
| PRRSV | Porcine reproductive and respiratory syndrome virus |
| PTM | Post-translational modification |
| RBR | RING-between-RING |
| RIG-I | Retinoic acid-inducible gene I |
| RING | Really interesting new gene |
| RLR | RIG-I-like receptor |
| RNF125 | RING finger protein 125 |
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 |
| SeV | Sendai virus |
| siRNA | Small interfering RNA |
| ssDNA | Single-stranded DNA |
| ssRNA | Single-stranded RNA |
| STAT1/STAT2 | Signal transducer and activator of transcription 1/2 |
| STING | Stimulator of interferon genes |
| TBK1 | TANK-binding kinase 1 |
| TF | Transcription factor |
| TNF-α | Tumor necrosis factor alpha |
| TRIM25 | Tripartite motif-containing protein 25 |
| UBA7 | Ubiquitin-like modifier-activating enzyme 7 |
| UbcH8 | Ubiquitin-conjugating enzyme human 8 |
| UbcM8 | Ubiquitin-conjugating enzyme mouse 8 |
| UBE1L | Ubiquitin-activating enzyme E1-like |
| UBE2L6 | Ubiquitin-conjugating enzyme E2-like 6 |
| UBL | Ubiquitin-like protein |
| USP18/USP24 | Ubiquitin-specific peptidase 18/24 |
| VACV | Vaccinia virus |