| BBB | Blood–Brain Barrier |
| CL | Cutaneous Leishmaniasis |
| CP | Cysteine Protease |
| HAT | Human African Trypanosomiasis |
| hCatB | Human Cathepsin B |
| hCatL | Human Cathepsin L |
| ML | Mucocutaneous Leishmaniasis |
| NTD | Neglected Tropical Disease |
| PAINS | Pan-Assay Interference Compounds |
| POI | Protein of Interest |
| PROTAC | Proteolysis Targeting Chimera |
| SAR | Structure–Activity Relationship |
| SI | Selectivity Index |
| VL | Visceral Leishmaniasis |
| VSG | Variant Surface Glycoprotein |
| WHO | World Health Organization |