3D	Three-dimensional
AAV	Adeno-associated virus
ABA	Applied behavior analysis
ABAS	Adaptive Behavior Assessment System
ABC	Aberrant Behavior Checklist
ABC-CT	Autism Biomarkers Consortium for Clinical Trials
ACB	Autologous cord blood
AD	Adipose tissue
ADDM	Autism and Developmental Disabilities Monitoring
ADI-R	Autism Diagnostic Interview-Revised
AD-MSC	Adipose tissue-derived mesenchymal stromal cell
Akt	Protein kinase B
AM	Amniotic membrane
Anti-HBc	Hepatitis B core antibody
Anti-HBs	Hepatitis B surface antibody
APRICOT	Anaesthesia PRactice In Children Observational Trial
ARDS	Acute respiratory distress syndrome
ASD	Autism spectrum disorder
ATEC	Autism Treatment Evaluation Checklist
ATMP	Advanced therapy medicinal product
B7-H1	B7 homolog 1
Bax	Bcl-2-associated X protein
BBB	Blood–brain barrier
BDNF	Brain-derived neurotrophic factor
BEST	Biomedical Excellence for Safer Transfusion
BM	Bone marrow
BMMNC	Bone marrow mononuclear cells
BM-MSC	Bone marrow-derived mesenchymal stromal cell
CARS	Childhood Autism Rating Scale
CARS-2	Childhood Autism Rating Scale, Second Edition
Caspase	Cysteine-aspartic protease
CBMNC	Cord blood mononuclear cell
CBT	Cognitive behavioral therapy
CD	Cluster of differentiation
CDC	Centers for Disease Control and Prevention
CFU-F	Colony-forming unit-fibroblast
CGI	Clinical Global Impression
cGMP	Current Good Manufacturing Practice
CI	Confidence interval
CNS	Central nervous system
COVID-19	Coronavirus disease 2019
CP	Cerebral palsy
CSF	Cerebrospinal fluid
CUMS	Chronic unpredictable mild stress
Denver II	Denver Developmental Screening Test, Second edition
DMSO	Dimethyl sulfoxide
EBMT	European Society for Blood and Marrow Transplantation
EEG	Electroencephalography
EGF	Epidermal growth factor
EOWPVT	Expressive One Word Picture Vocabulary Test, Fourth edition
EP2	Prostaglandin E2 receptor subtype 2
EP4	Prostaglandin E2 receptor subtype 4
EV	Extracellular vesicles
FBS	Fetal bovine serum
FDA	Food and Drug Administration
FGF	Fibroblast growth factor
FIM	Functional Independence Measure
FLT1	Fms-related tyrosine kinase 1
FMEA	Failure mode and effects analysis
FoxP3	Forkhead box P3
GABA	Gamma-aminobutyric acid
GAG	Glycosaminoglycan
GAP-43	Growth-associated protein 43
GARS-II	Gilliam Autism Rating Scale, Second Edition
GDNF	Glial cell line-derived neurotrophic factor
GM-CSF	Granulocyte-macrophage colony-stimulating factor
GMFM-66	Gross Motor Function Measure-66
GMP	Good Manufacturing Practice
GVHD	Graft-versus-host disease
H&E	Hematoxylin and eosin
HBV	Hepatitis B virus
HCV	Hepatitis C virus
HGF	Hepatocyte growth factor
HIV	Human immunodeficiency virus
HLA	Human leukocyte antigen
HLA-ABC	Human leukocyte antigen class I (A, B, and C)
HLA-DR	Human leukocyte antigen-DR isotype
HLA-G	Human leukocyte antigen-G
HPL	Human platelet lysate
HTLV	Human T-cell lymphotropic virus
HUCPV	Human umbilical cord perivascular
ICS	Individualized combination supplements
ICV	Intracerebroventricular
ID	Intellectual disability
IDO	Indoleamine 2,3-dioxygenase
IFNG-AS1	Interferon gamma antisense RNA 1
IFN-γ	Interferon-gamma
IGF-1	Insulin-like growth factor-1
IGF-1R	Insulin-like growth factor-1 receptor
IL	Interleukin
IL-1Ra	Interleukin-1 receptor antagonist
iPSC	Induced pluripotent stem cell
IQ	Intelligence Quotient
ISAA	Indian Scale for Assessment of Autism
ISCT	International Society for Cellular Therapy
IT	Intrathecal
IV	Intravenous
JAKE	Janssen Autism Knowledge Engine
LPS	Lipopolysaccharide
MAPC	Multipotent adult progenitor cell
MCB	Master cell bank
MCP-1	Monocyte chemoattractant protein-1
MDC	Macrophage-derived chemokine
MHC	Major histocompatibility complex
MIA	Maternal immune activation
miR-21a-3p	MicroRNA-21a-3p
MMP	Matrix metalloproteinase
mRNA	Messenger RNA
MSC	Mesenchymal stromal cell
MSEC	Mental Synthesis Evaluation Checklist
mTOR	Mechanistic target of rapamycin
NAT	Nucleic acid testing
NF-κB	Nuclear factor kappa B
NGF	Nerve growth factor
NK	Natural killer
NLRP3	Nucleotide oligomerization domain-like receptor protein 3
NOD	Non-obese diabetic
NSE	Neuron-specific enolase
NT-3	Neurotrophin-3
OA	Osteoarthritis
OCT	Octamer-binding transcription factor
OMI	Oculomotor Index of Gaze to Human Faces
PACT	Production Assistance for Cellular Therapies
PDD	Pervasive Developmental Disorder
PDGF	Platelet-derived growth factor
PDMS-2	Peabody Developmental Motor Scales-2 Gross Motor Quotient
PET	Positron emission tomography
PGE2	Prostaglandin E2
pHPL	Pooled human platelet lysate
PI3K	Phosphoinositide 3-kinase
Poly I:C	Polyinosinic-polycytidylic acid
PTEN	Phosphatase and tensin homolog
PV	Perivascular
RBS-R	Repetitive Behavior Scale-Revised
RCT	Randomized controlled trial
RDoC	Research Domain Criteria
REX1	Reduced expression protein 1
RORγt	Retinoic acid receptor-related orphan nuclear receptor gamma t
RR	Relative risk
SA	Sub-amnion
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2
SCID	Severe combined immunodeficiency
SCQ	Social Communication Questionnaire
SEED	Study to Explore Early Development
SMD	Standardized mean difference
SOX	SRY-box transcription factor
SRS	Social Responsiveness Scale
SSEA	Stage-specific embryonic antigen
SSRI	Selective serotonin reuptake inhibitor
STR	Stirred-tank bioreactor
SYP	Synaptophysin
TARC	Thymus and activation-regulated chemokine
TGF-β1	Transforming growth factor-beta 1
Th	T-helper
TLR	Toll-like receptor
TNCC	Total nucleated cell count
TNF-α	Tumor necrosis factor-alpha
Treg	Regulatory T cell
TREM-2	Triggering receptor expressed on myeloid cells-2
TRM	Treatment-related mortality
TSPO	Translocator protein
UCB	Umbilical cord blood
UC-MSC	Umbilical cord-derived mesenchymal stromal cell
US	United States
USV	Ultrasonic vocalization
VABS-3	Vineland Adaptive Behavior Scales, Third Edition
VABS-II	Vineland Adaptive Behavior Scales, Second Edition
VEGF	Vascular endothelial growth factor
VPA	Valproic acid
WeeFIM	Functional Independence Measure for Children
WHO	World Health Organization
WJ	Wharton’s jelly
WJ-MSC	Wharton’s jelly-derived mesenchymal stromal cell
WMD	Weighted mean difference
WOMAC	Western Ontario and McMaster Universities Osteoarthritis Index total outcomes