| AA | Antioxidant activity |
| ALT | Alanine aminotransferase |
| ANOVA | Analysis of variance |
| AST | Aspartate aminotransferase |
| ATCC | American Type Culture Collection |
| BSLE | Brugmansia suaveolens hydroethanolic leaf extract |
| BSLE-NE | Nanoemulsion containing Brugmansia suaveolens hydroethanolic leaf extract |
| CAPES | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
| CEUA | Ethics Committee on Animal Use |
| CFU | Colony-forming units |
| CC50 | Concentration causing 50% reduction in cell viability |
| CC90 | Concentration causing 90% reduction in cell viability |
| DLS | Dynamic light scattering |
| DMEM | Dulbecco’s Modified Eagle Medium |
| DPPH | 2,2-Diphenyl-1-picrylhydrazyl |
| EC50 | Half-maximal effective concentration |
| FAPERJ | Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro |
| FBS | Fetal bovine serum |
| GC–MS | Gas chromatography coupled to mass spectrometry |
| H&E | Hematoxylin and eosin |
| HaCaT | Human keratinocyte cell line |
| HFB | Human fibroblasts |
| ISO | International Organization for Standardization |
| J774 | Murine macrophage cell line |
| logKp | Skin permeability coefficient |
| LogP | Partition coefficient |
| m/z | Mass-to-charge ratio |
| NADH | Reduced nicotinamide adenine dinucleotide |
| NIST | National Institute of Standards and Technology |
| Pa | Probability of activity |
| PARNASO | Serra dos Órgãos National Park |
| PASS | Prediction of Activity Spectra for Substances |
| PDI | Polydispersity index |
| Pi | Probability of inactivity |
| RI | Retention index |
| SD | Standard deviation |
| SISGEN | Brazilian National System for the Management of Genetic Heritage and Associated Traditional Knowledge |
| TEM | Transmission electron microscopy |
| TMS | Trimethylsilyl |
| TPSA | Topological polar surface area |
| UFRJ | Federal University of Rio de Janeiro |
| UHPLC–ESI–QTOF–MS | Ultra-high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry |
| UHPLC–MS | Ultra-high-performance liquid chromatography coupled with mass spectrometry |
| UNIFESO | Centro Universitário Serra dos Órgãos |