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SANS data for Tn3R in solution. (A) Experimental (circles) and simulated (dashed and solid lines) SANS curves (see text for more details). (B–C) Structural models for dimeric Tn3R in solution were generated by using the protein component of the co-crystal structure 1gdt (dashed line, panel B11) and a modified version in which the DNA-binding domains of Tn3R were extended in an open conformation (see Materials and Methods; solid line, Tn3R-ext, panel C).
