TABLE 1.

Parameters from global fits to model I

Residue*	We (MHz)	T1e (μs)	kex2(O2) (MHz/mM)	kex3 (NiEDDA) (MHz/mM)	χ2†
128	0.23	2.1	1.75	0.13	1.94
129	0.09	5.5	0.28	0.008	2.15
130	0.21	2.4	1.52	0.11	2.34
131	0.25	2.0	1.55	0.17	2.22
132	0.26	1.9	1.75	0.22	1.70
133	0.06	7.9	0.15	0.0008	2.13
134	0.13	3.9	1.13	0.12	3.04
135	0.24	2.1	0.53	0.06	2.78

^*The specific exchange rate constants (k_ex) are obtained by dividing W_ex values obtained from fitting by the concentration of exchange reagent, 3 mM for NiEDDA, and 0.26 mM for O₂ (38).

^†From global fits.