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. 2005 Jun 10;89(5):2911–2926. doi: 10.1529/biophysj.105.060913

TABLE 3.

Model parameters

Parameter Definition Comments
EIMT Flexural rigidity of a microtubule. Used to calculate all elastic properties of tubulin in the model.
k(+) Bimolecular on rate constant. Required constant to predict k(−) at various microtubule tip sites.
ΔG°Lat Standard free energy change for lateral association. Antagonized by ΔG°curl for tubulin-GDPs.
Inline graphic Standard free energy change of longitudinal association plus the free energy of immobilizing a dimer in the microtubule lattice. Requires the assumption that dimers in the microtubule lattice always have at least one longitudinal bond.
kH Hydrolysis rate constant. Only for dimers with tubulin bound to their β-tubulin end.