TABLE 3.

Rate constants for Kv4.3 Markov model (Scheme 2)

α[V] = (1/(1 + Exp[(V + 10.0)/10.0]))*(0.425*Exp[0.27*V*0.03918]*

Exp[(V + 10.0)/10.0] + 0.0836*Exp[0.83*V*0.03918]).

β[V] = (1/(1 + Exp[(V + 5.0)/10.0]))*(0.2244*Exp[−0.54*V*0.03918]*

Exp[(V + 5.0)/10.0] + 0.0252*Exp[−0.48*V*0.03918]).

K1 = 6

K2 = 1.5

K3 = 0.021

K4 = 0.007

K5 = 0.0052

K6 = 0.000052

K7 = 0.0052

K8 = 0.0036

K9 = 0.0009

K10 = 0.04

K11 = 0.249941

K12 = 0.000975

Rate constants are expressed as s−1.