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(A) Representative single-channel currents obtained from a series of six side-chain substitutions at position δ268. Currents were elicited with saturating choline (20 mM) in a wild-type background. Openings are downwards. Capital letters indicate the identity of the substitution at δS268. (B) Open and closed time histograms and fitted probability density function of the δ268I mutant series.
