TABLE 3.
Recovered amide I components dichroic ratios for fusion peptides
| gp41 (pD 7.5)*
|
HA (pD 5.5)
|
||||
|---|---|---|---|---|---|
| POPC | DOPC/DOPE/SM/CH | POPC | DOPC/DOPE/SM/CH | ||
| 1614 cm−1 | RZ | 1.4 ± 0.9 | 0.9 ± 0.2 | – | – |
| % | 3.8 ± 0.4 | 2.6 ± 0.2 | – | – | |
| 1625 cm−1 | RZ | 1.2 ± 0.2 | 1.4 ± 0.4 | – | 1.2 ± 0.0 |
| % | 35.9 ± 2.7 | 20.3 ± 5.3 | – | 19.0 ± 7.2 | |
| 1632 cm−1 | RZ | 2.0 ± 0.4 | 1.7 ± 0.1 | – | – |
| % | 10.0 ± 1.1 | 13.4 ± 1.8 | – | – | |
| 1649 cm−1 | RZ | 1.9 ± 0.4 | 1.7 ± 0.1 | 1.8 ± 0.0 | 1.7 ± 0.1 |
| % | 22.1 ± 1.2 | 30.2 ± 3.0 | 81.5 ± 1.1 | 73.1 ± 6.4 | |
| 1677 cm−1 | RZ | 2.1 ± 1.2 | 1.7 ± 0.2 | 1.8 ± 0.0 | 1.9 ± 0.0 |
| % | 13.5 ± 1.3 | 25.3 ± 4.7 | 6.2 ± 0.2 | 7.9 ± 3.2 | |
| 1688 cm−1 | RZ | 3.3 ± 1.7 | 2.0 ± 0.4 | – | – |
| % | 6.9 ± 0.0 | 4.4 ± 0.7 | – | – | |
| Minor components | % | 7.8 | 3.8 | 12.3 | 0.0 |
*
Values listed are the average and range of two measurements. The β-sheet orientation, γ, is calculated as described in methods. Percentages in each column are amide I component areas and total 100%.