Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2026 Oct 1;16:1919412. doi: 10.3389/fonc.2026.1919412

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2026 Yang, Li, Jiang, Deng, Tan, Zhu, Li, Wang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Four-panel scientific figure showing: A, a UMAP plot colored by cell type for single-cell atlas annotation; B, six UMAP plots with red-to-blue gradients for distinct immune program scores; C, a bubble plot mapping cell-type program profiles; D, six corresponding heatmaps for donor-resolved program profiles. — Single-cell contextualization of the six composite programs. (A–D) UMAP, standardized UCell overlays, annotation-resolved profiles and donor-resolved descriptive summaries for 14,368 DLBCL cells from four patients, eight samples and nine retained annotations. Among retained annotations, Stromal/fibrotic scores were highest in monocytes/macrophages. Fibroblast and endothelial annotations were absent, preventing direct testing of stromal-lineage localization. Panel (C) dot size is the within-annotation fraction above the program-specific 75th percentile, not tissue abundance. B-cell-sorted and non-B-cell-sorted samples are both represented. No reannotation, malignant-cell inference or taxonomy validation was performed.