Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Posaconazole pharmacokinetic parameters on day 3
| Parameter (units) | Value [mean (% coefficient of variation)]
|
||
|---|---|---|---|
| Group 1 (200 mg q.i.d.) (n = 24) | Group 2 (400 mg q.i.d.) (n = 21) | Group 3 (800 mg b.i.d.) (n = 24) | |
| Cmax (ng/ml) | 539 (82) | 531 (71) | 417 (60) |
| Cav (ng/ml) | 447 (84) | 423 (70) | 340 (63) |
| Tmaxa (h) | 2.65 (0, 11.8) | 5.78 (2, 12.4) | 4.21 (0, 11.9) |
| AUC(0-12) (ng · h/ml) | 5,314 (83) | 5,075 (71) | 4,035 (63) |
Median (minimum, maximum).
