TABLE 2.

Effect of pH on properties of peptide binding to a bilayer membrane^a

^aThe cartoon illustrates our interpretation of the binding events according to the two-step binding model. Adhesion to a negatively charged surface (upper drawing) is followed by insertion (lower drawing) into the membrane hydrophobic core. The table summarizes SPR data obtained using a PC-PG (3:1) membrane. Values represent the means and standard deviations obtained from three independent experiments performed in duplicates. χ² is indicative of the level of fitting of the binding model to the measured data and is lowest for optimal fit.