TABLE 1.

Simulated pharmacokinetic parameters

Dose fractionation group	AMB dose (mg/kg) and interval	Cmax (μg/ml) (first dose)	AUC24 (μg · h/ml)
0.5 mg/kg	0.167 q8h	0.07	2.9
	0.5 q24h	0.20	3.1
	1.5 q72h	0.60	3.4
0.75 mg/kg	0.25 q8h	0.10	4.3
	0.75 q24h	0.30	4.7
	2.25 q72h	0.89	5.1
1.0 mg/kg	0.33 q8h	0.13	5.7
	1.0 q24h	0.40	6.3
	3.0 q48h	1.2	6.9