TABLE 1.
Tissue | % of spiked drug concn recovered in homogenate supernatant
|
||||||||
---|---|---|---|---|---|---|---|---|---|
Amphotericin B
|
L-AMB
|
ABLC
|
|||||||
80 μg/ml | 20 μg/ml | 5 μg/ml | 80 μg/ml | 20 μg/ml | 5 μg/ml | 80 μg/ml | 20 μg/ml | 5 μg/ml | |
Kidney | 25 | 23 | 30 | 90 | 98 | 93 | 2 | 5 | 6 |
Liver | 25 | 21 | 32 | 100 | 100 | 100 | 1 | 2 | 1 |
Lung | 12 | 9 | 19 | 100 | 100 | 100 | 1 | 2 | 2 |