Microscopic length scale |
λ |
m |
Diffusion coefficient |
D |
m2 s−1
|
Microscopic diffusion timescale |
δt = λ2/4D
|
s |
Association rate |
k+
|
M−1 s−1
|
Dissociation rate |
k− |
s−1
|
Equilibrium dissociation constant |
|
M |
Mean surface density of receptors |
R0
|
No. of molecules/m2
|
Surface density of receptors inside clusters |
R′0
|
No. of molecules/m2
|
Bound receptor fraction at time t
|
p(t) |
Dimensionless |
Ligand density profile close to the surface at time t
|
ρ(t) |
No. of molecules/m3
|
Return to origin probability density for a surface with R0 receptors per unit area |
|
m−1
|
Return to origin probability density for a perfectly absorbing surface |
q(t) |
m−1
|
Probability of nonabsorption upon contact |
γ |
Dimensionless |
Timescale of exponential decay (Eq. 11a) |
te
|
s |