TABLE 1.

Results of build-up procedure (starting from residue 170) of geometrical sampling for the EC2 loop

*	179	181	183	185	187	189	191	193	195	197	200
†	5.0	5.0	5.0	5.0	5.0	5.0	8.0	8.0	8.0	8.0	8.0
‡	0.0	2.0	5.0	3.0	3.0	−5.0	−5.0	−2.0	−2.0	−2.0	0.0
§	4,380	16,715	275,000	333,080	690,570	3,915	7,400	40,950	79,005	56,905	2,155

^*End residue of a fragment.

^†D_out at a given step, Å.

^‡DEL at a given step, Å.

^§Number of selected loop-closing backbone conformers.