TABLE 1.
Mean molecular weight, degree of polymerization, and molar ratio of the poly-L-amino acids used
| Polypeptide | Shorthand notation | (〈Mw〉vis (kDa) | Dp | Molar ratio |
|---|---|---|---|---|
| Poly-L-lysine HCl | Kn | 52.5 | 319 | — |
| Co-poly-L-(lysine, phenylalanine) 1:1 HBr | (KF)n | 49.0* | 275* | 52:48 |
| 42.2† | 237† | 52:48 | ||
| Co-poly-L-(lysine, tyrosine) 1:1 HBr | (KY)n | 128 | 684 | 53:47 |
| Co-poly-L-(lysine, tyrosine) 4:1 HBr | (K4Y)n | 24.6 | 123 | 80:20 |
The degree of polymerization, Dp, refers to the number of amino acid residues in each peptide chain.
*
Used for NMR and binding isotherm.
†
Used for all other studies.