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Parameters related to IP3 dynamics given by Eq. 11
| Parameter | Description | Value |
|---|---|---|
| PMV | Maximal rate of voltage-dependent IP3 synthesis | 0.8 μM/min |
| kV | Half saturation constant for voltage-dependent IP3 synthesis | −58 mV |
| r | Hill coefficient | 8 |
| β | External stimulus generated IP3 | See text (μM/min) |
| ɛ | Rate constant for linear IP3 degradation | 0.9 min−1 |
| PM4 | Maximal value for the nonlinear IP3 degradation | 2 μM/min |
| k4 | Half saturation constant for the nonlinear IP3 degradation | 0.5 μM |
| u | Hill coefficient | 4 |
