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Sequence of SP-B-derived peptides. Amino-acid sequence of human SP-B and the SP-B-derived synthetic peptides studied in this work. Shaded boxes represent proposed helical regions, and black lines the predicted interhelical loops derived by fitting the sequence of the SP-B mature peptide to the three-dimensional structure of NK-lysin (9). Amino-acid substitutions in the variant synthetic peptides appear shaded. Note that the exact boundaries of these domains remain unclear.
