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. 2026 Jul 17;23:100. doi: 10.1186/s12981-026-00925-x

Table 1.

Patient-index demographic profile and diagnostic spectrum (one earliest record per patient; n = 581)

Diagnostic group (index) Patients, n % of patients (95% CI) Female, n (%) Age, years, median (IQR)
Opportunistic CNS infection 206 35.5 (31.7–39.4) 94 (45.6) 42 (35–49)
HIV-attributed/organic CNS (HAND/HIV-CNS) 148 25.5 (22.1–29.2) 111 (75.0) 41 (33–51)
Major depressive disorder 138 23.8 (20.5–27.4) 98 (71.0) 47 (35–53)
Bipolar spectrum disorder 40 6.9 (5.1–9.2) 27 (67.5) 48 (42–57)
Anxiety / stress-related 17 2.9 (1.8–4.6) 9 (52.9) 33 (19–47)
Dementia spectrum 15 2.6 (1.6–4.2) 4 (26.7) 63 (57–65)
Psychosis spectrum 12 2.1 (1.2–3.6) 5 (41.7) 41 (35–57)
Substance use disorder 4 0.7 (0.3–1.8) 3 (75.0) 41 (31–51)
Other neurological / medical 1 0.2 (0.0–1.0) 1 (100.0) 66
Total 581 100 352 (60.6) 44 (35–52)

CI confidence interval (Wilson), IQR interquartile range. Percentages of patients use the full denominator of 581. Female percentage is within each diagnostic group