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. 2005 Oct 28;90(2):681–692. doi: 10.1529/biophysj.105.061010

FIGURE 6.

FIGURE 6

Comparison of the thermal method and the stretch method. Molecular spring constants of (A) P-selectin and (B) L-selectin bound with (s)PSGL-1 or their respective mAb. Data are presented as mean ± SE of n (indicated by numbers over the error bars) independent measurements. The p-values comparing the spring constants (obtained by the stretch method) when the selectin was varied are ≪0.001 for both pairs of P-selectin-sPSGL-1 versus L-selectin-PSGL-1 and P-selectin-G1 versus L-selectin-DREG56. The respective p-values comparing the spring constants (obtained by the thermal method) when the (s)PSGL-1 was changed to mAb are 0.86 and 0.27 for the pairs of P-selectin-sPSGL-1 versus P-selectin-G1 and L-selectin-PSGL-1 versus L-selectin-DREG56, respectively.