Skip to main content
. 2002 Dec;76(24):12423–12434. doi: 10.1128/JVI.76.24.12423-12434.2002

FIG.6.

FIG.6.

Follow-up analysis of HBV- and HCV-specific CD8 cell frequency and function. The analyses were performed at two different time points (6 to 16 weeks and 24 to 30 weeks after clinical presentation). (A and B) Frequencies and perforin contents of tetramer-positive HBV- and HCV-specific CD8 cells ex vivo. (C, D, E, and F) Capacities for expansion, perforin expression, IFN-γ production, and cytolytic activity after 10 days of stimulation with peptide. (C) Each bar represents the percentage of tetramer-positive cells calculated based on the total number of CD8 cells. (D and E) Each bar represents the percentage of perforin-positive and IFN-γ positive cells, respectively, among the overall population of HBV or HCV tetramer-positive CD8 lymphocytes. (F) The bars represent the percentages of specific lysis expressed by CD8 cells against peptide-pulsed target cells. ∗, frequency of tetramer-positive cells was <0.01% of CD8+ cells; nt, not tested.