TABLE 2.
Demographic, virologic, and biochemical characteristics of patients with acute HCV infectiona
| Patient | Genotype | Age (yr) | Sex | 1st time point
|
2nd time point
|
3rd time point
|
Outcome | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Wk from clinical presentation | AST/ALT | HCV RNA (copies/ml) | Wk from clinical presentation | HCV RNA (copies/ml) | AST/ALT | Wk from clinical presentation | HCV RNA (copies/ml) | AST/ALT | |||||
| 1C | 1b | 58 | F | 1 | 177/875 | <2,500 | 14 | <2,500 | 19/17 | 25 | <2,500 | 13/11 | Self-limited |
| 2C | 3a | 26 | M | 5 | 13/69 | <2,500 | 16b | 324,449 | 23/100 | 30 | 305,202 | 20/63 | Chronic |
| 3C | 3a | 25 | M | 1 | 123/356 | <2,500 | 9 | <2,500 | 23/31 | 29 | <2,500 | 28/32 | Self-limited |
| 4C | 1a | 34 | M | 2 | 125/336 | 71,891 | 12 | 9,150 | 29/182 | 40 | 171,545 | 33/55 | Chronic |
| 5C | 3a | 27 | F | 1 | 1,120/2,190 | ND | 14b | ND | 18/30 | 30 | 184,356c | 233/388 | Chronic |
| 6C | 1b | 33 | M | 2 | 52/277 | 2,533 | 13 | 398,209 | 44/83 | 26b | 2,263,736 | 44/145 | Chronic |
| 7C | 3a | 30 | M | 1 | 50/269 | ND | 16b | <2,500 | 32/27 | 80 | <2,500 | 17/9 | Self-limited |
Patients were studied at three different time points of the follow-up. ND, not determined; F, female; M, male. The lower limit of detection for HCV RNA is 2,500 copies/ml.
No immunological analysis performed in parallel.
Viremia evaluated at a later time point relative to immunological analysis.