Experimental trajectory (120 s) of a μ-opioid receptor at the surface of a normal rat kidney cell (5), truncated in successive 20-s segments shown in different colors (indigo, cyan, green, yellow, orange, red) to highlight the displacement of the confining domain of size L ≅ 500 nm, in which the receptor diffuses rapidly. The black trajectory shows the slow diffusion of the barycenter of this domain calculated on sliding 4-s intervals.