TABLE 1.

Pulse protocols in OHCs: comparison of absolute TMP at onset of EP

Location	Stimulus polarity	Absolute TMP at onset of EP
Basal	Hyperpolarizing	388 ± 21 (n = 10)
	Depolarizing	382 ± 14 (n = 10)
Lateral	Hyperpolarizing	388 ± 13 (n = 10)
	Depolarizing	446 ± 20 (n = 10)

OHCs demonstrated a statistically significant difference in susceptibility to EP due to the effect of polarity at the lateral PM (p <.05, t-test). The incidence of EP was 100% in all categories. The charge density of the guinea pig OHCs lateral wall is estimated to be ∼150–200 fC/pF.