TABLE 2.

Pulse protocols in gPres transfected and nontransfected TSA cells: incidence of EP, absolute TMP at onset of EP

DNA	Stimulus polarity	EP incidence	Absolute TMP at onset of EP (mV)	Charge density
None	Hyperpolarizing	90% (n = 10)	464 ± 20	N/A
	Depolarizing	90% (n = 10)	495 ± 13	N/A
gPres	Hyperpolarizing	100% (n = 9)	549 ± 50	13.1 ± 3.1 fC/pF
	Depolarizing	44% (n = 9)	600 ± 122	14.5 ± 10.6 fC/pF

Transfected TSA cells demonstrate significantly reduced EP incidence with depolarizing 50 ms pulse trains (p < .02, chi-square analysis). No statistically significant differences are evident comparing absolute TMP at onset of EP.