FIG. 1.

As₂O₃ counteracts HIV-1 restriction in Vero and TE671 cells but not in CV1, OMK, or FRhK4 cells. Cells were infected with VSV-G-pseudotyped HIV-1_NL4-3 bearing an env deletion and GFP in place of nef (HIV-1_GFP), such that <5% of target cells were infected. The indicated concentrations of As₂O₃ were maintained for the first 12 h that cells were exposed to the virus, at which time the medium was replaced without the drug. The percentage of GFP-positive (infected) cells was determined at 48 h postinfection by flow cytometry.