TABLE 3.
MAb | Quantity of MAb administered (μg) | % of surviving animals | Mean time of death (days) |
---|---|---|---|
None (control) | 0 | 7.5 | |
Nip GIP 1.7 (anti-NiV.G) | 112 | 100 | |
1.12 | 100 | ||
0.12 | 25 | 10.5 | |
0.012 | 25 | 12.5 | |
0.0012 | 25 | 9.5 | |
Nip GIP 35 (anti-NiV.F) | 180 | 100 | |
1.8 | 50 | 11.5 | |
0.18 | 0 | 7.75 | |
0.0.18 | 0 | 6.75 | |
0.0018 | 0 | 6.75 |
Hamsters (four animals per group) were given dilutions of MAbs 24 h prior to and 1 h after receiving a lethal challenge of NiV.