TABLE 2.
IFN-γ ELISPOT response in monkeys infected with SHIV 89.6P
| Monkey | No. of spot-forming cells/106 PBMC in response to the indicated antigen at the following day postchallenge:
|
|||||
|---|---|---|---|---|---|---|
| Day 24
|
Day 73
|
|||||
| Medium | KDa | p11CM | Medium | KD | p11CM | |
| Mamu-A*01+ | ||||||
| AW80 | 0 | 22 | 352 | 0 | 3 | 175 |
| AW9C | 0 | 110 | 2,912 | 3 | 218 | 1,755 |
| CB8P | 2 | 25 | 2,425 | 0 | 48 | 1,083 |
| CC7J | 2 | 10 | 2,048 | 0 | 5 | 348 |
| Mamu-A*01− | ||||||
| CC6F | 0 | 10 | 2 | 5 | 5 | 5 |
| CC6P | 2 | 32 | 2 | 13 | 8 | 0 |
| 99D221 | 0 | 8 | 0 | NTb | NT | NT |
| 99D149 | 0 | 58 | 10 | NT | NT | NT |
a
KD, a pool of overlapping peptides covering the SIV gag open reading frame. The peptides containing the p11CM epitope sequence are omitted from the pool.
b
NT, not tested.