FIG. 9.

Cystine bridge model for Ebola virus GP and comparison of GP₂ to the Rous sarcoma virus GP TM subunit. Representational elements for the mucin-like region, the fusion peptides, the coiled-coil domains, and the membrane-spanning domains are identical to those used in Fig. 1. (A) The cystine bridge arrangement in the Ebola virus GP deduced from the results presented here and elsewhere (10, 16, 36) and the critical N-glycosylation sites (Y) discussed in the text are depicted. (B) A proposed cystine bridge model for the TM protein of Rous sarcoma virus (an ASLV) (3, 10) is presented for comparison with that for Ebola virus GP₂.