TABLE 4.

Reference energies for all 10 uniquely defined nearest-neighbor pairs

Nearest neighbor	AVG (kcal/mol)	STDEV	No. points	Santa Lucia (kcal/mol)
C-C	−86.199	3.683	120	−11.1
C-G	−79.877	4.24	133	−10.1
A-C	−79.483	3.198	103	−8.4
G-G	−78.231	3.908	123	−8.6
A-G	−74.436	3.521	113	−7.4
A-A	−72.789	3.594	32	−7.7
C-T	−71.678	3.504	111	−6.7
G-T	−67.92	3.169	103	−6.3
A-T	−64.803	3.664	84	−6.5
T-T	−58.423	2.885	32	−6.1