TABLE 2.
Flexural rigidity of microtubules obtained with different experimental methods
| Microtubules | Methods | Flexural rigidity (× 10−24 Nm2) | Temperature (°C) | References |
|---|---|---|---|---|
| Paclitaxel-free MT (Pure MT)
|
Buckling force | 7.9 | 33 | This work |
| Buckling force | 6.8 | (4) | ||
| Hydrodynamic flow | 8.5 | 37 | (7) | |
| Hydrodynamic flow | 35.8 | 37 | (8) | |
| Relaxation (RELAX) | 3.7 | 22–25 | (5) | |
| Relaxation (WIGGLE) | 4.7 | 22–25 | (5) | |
| Thermal fluctuation | 26.0 | 37 | (11) | |
| Thermal fluctuation | 4.6 | 37 | (7) | |
| Thermal fluctuation | 26.5* | 37 | (8) | |
| Thermal fluctuation | 18.5 | (12) | ||
| Thermal fluctuation
|
13.7–27.0*
|
23
|
(13)
|
|
| Paclitaxel-stabilized MT
|
Buckling force | 2.0 | 33 | This work |
| Buckling force | 2.0–22 | 37 | (3) | |
| Buckling force | 2.4 | (4) | ||
| Relaxation (RELAX) | 1.0 | 22–25 | (5) | |
| Relaxation (WIGGLE) | 1.9 | 22–25 | (5) | |
| Thermal fluctuation | 21.5 | 25 | (9) | |
| Thermal fluctuation | 32.0 | 37 | (11) | |
| Thermal fluctuation | 2.4 | 37 | (7) |
*
These values of EI were calculated from the measured values of persistence length, Lp (EI = kBT Lp).