TABLE 2.
Base and amino acid substitutions found by comparing the complete DNA sequences of V-Oka and P-Okaa
| Positionb | Gene | Amino acid substitution(s)
|
|
|---|---|---|---|
| V-Oka | P-Oka | ||
| 560 | 5′ noncoding | C (NCR) | T (NCR) |
| 703 | 1 | T/C (Gln) | T (Gln) |
| 763 | 1 | T/C (Pro) | T (Pro) |
| 2515 | 3/4 | T/C (NCR) | T (NCR) |
| 5745 (945) | 6 | G (Pro) | A (Ser) |
| 10900 (91) | 9A | T/C (Trp/Arg) | T (Trp) |
| 12779 (207) | 10 | T/C (Ala/Val) | T (Ala) |
| 19431 | 14 | T/C (OCH/AMB) | T (OCH) |
| 26125 | 18 | G (Asn) | A (Asn) |
| 31732 (325) | 21 | T/C (Thr/Ile) | C (Thr) |
| 38036 | 22 | T/C (Thr) | T (Thr) |
| 39227 | 22 | T/G (Pro) | T (Pro) |
| 58595 (530) | 31 | A/G (Ile/Val) | A (Ile) |
| 59287 | 31 | A/G (Pro) | A (Pro) |
| 64067 | 35 | A/G (Ala) | A (Ala) |
| 71252 (207) | 39 | T/C (Met/Thr) | T (Met) |
| 82225 | 45 | A/G (Pro) | A (Pro) |
| 84091 | 47 | A/G (Glu) | G (Glu) |
| 87280 | 50 | A/G (Cys) | A (Cys) |
| 87306 (193) | 50 | T/C (Ser/Gly) | T (Ser) |
| 89734 | 51 | A/G (Thr) | A (Thr) |
| 90535 (15) | 52 | A/G (Ile/Val) | A (Ile) |
| 94167 | 54 | C (Leu) | T (Leu) |
| 97748 (585) | 55 | G/A (Ala/Thr) | G (Ala) |
| 97796 (601) | 55 | T/C (Cys/Arg) | T (Cys) |
| 101089 (44) | 59 | A/G (Leu/Pro) | A (Leu) |
| 105169 | 61/62 | A/G (NCR) | A (NCR) |
| 105310 (1275) | 62 | A/G (Leu/Ser) | A (Leu) |
| 105356 (1260) | 62 | C (Val) | T (Ile) |
| 105544 (1197) | 62 | G (Ala) | A (Val) |
| 105705 | 62 | C (Ala) | T (Ala) |
| 106262 (958) | 62 | C (Gly) | T (Arg) |
| 106710 | 62 | A/G (Ala) | A (Ala) |
| 107136 | 62 | C (Ala) | T (Ala) |
| 107252 (628) | 62 | C (Gly) | T (Ser) |
| 107599 (512) | 62 | A/G (Val/Ala) | A (Val) |
| 107797 (446) | 62 | A/G (Leu/Pro) | A (Leu) |
| 108111 | 62 | C (Pro) | T (Pro) |
| 108838 (99) | 62 | A/G (Met/Thr) | A (Met) |
| 109137 | 62/63 | A/G (NCR) | A (NCR) |
| 109200 | 62/63 | A/G (NCR) | A (NCR) |
| 111650 (29) | 64 | A/G (Gln/Arg) | A (Gln) |
a
Mutations in the repeat region are not shown here (see Fig. 2). The number at the base position refers to the sequence analysis of the Dumas virus. Base substitutions leading to amino acid conversions are indicated by filled cells. P-Oka has a base identical to that in the Dumas virus at every position. NCR, noncoding region; OCH, ocher; AMB, amber.
b
Numbers in parentheses refer to the amino acid number within a particular ORF.