TABLE 1.
Monkey | Virus or vaccine | No. of CD4+ T lympho- cytes (μl) | Plasma viral load (RNA copies/ml) | Duration of infection (days) |
---|---|---|---|---|
138-88 | SIVmac251 | 135 | <500 | 2,860 |
93-98 | SIVmac251 | 695 | <500 | 850 |
191-96 | SIVmac251 | 450 | <500 | 1,275 |
94-98 | SIVmac251 | 206 | <4,091 | 850 |
154-97 | SIVmac251 | 244 | 1,368 | 1,550 |
403-91 | SIVmac251(J5) | 479 | <500 | 3,315 |
448-98 | SIVmac251 | 590 | <500 | NAc |
253-96 | SIVmac251 | 637 | 839 | 1,315 |
88-98 | SIVmac251 | 84 | 1,030,655 | 1,215 |
H547 | SHIV 89.6P | 213 | 55,023 | 580 |
H544 | SHIV 89.6P | 804 | <500 | 580 |
AW2P | DNA/rAd5a | 1,328 | ||
AW28 | DNA/rAd5 | 2,401 | ||
90-98 | DNA/rMVAb | 1,190 | ||
95-98 | DNA/rMVA | 1,114 | ||
128-97 | DNA/rMVA | 1,889 | ||
135-97 | DNA/rMVA | 1,349 |
Immunized with plasmid DNA containing the SIVmac239 gag-pol-nef and HIV-1 89.6P env gene and boosted with recombinant adenovirus serotype 5 constructs expressing the SIV gag-pol-nef and HIV-1 89.6P env genes.
Immunized with plasmid DNAs containing the SIVmac239 gag, pol, and nef and the HIV-1 89.6 env epitope genes and boosted with recombinant MVA vectors expressing SIV gag-pol and HIV-1 89.6 env.
NA, data not available.