FIG. 5.
Recombination distribution throughout the full-length proviral genomic DNA. Ten out of 16 clones had undergone a total of 39 recombination events. Thirty-three out of the 39 recombinant sites were sequenced. Six putative hot spots are indicated by inverted triangles and summarized with stars. The coordinates of the putative hot spots are as follows: 333 to 421, 629 to 667, 831 to 870, 2683 to 2839, 4201 to 4312, and 5512 to 5539 (sequence coordinates are according to the HXB2 provirus sequence). White is of HIV-c-puroNL4-3 origin and grey is of HIV-gptHXB2 origin. The marker gene cassette is depicted in black.