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. 2026 Sep 19;18(9):e116527. doi: 10.7759/cureus.116527

Table 4. Joint association of obesity and glycemic control with incident abnormal uterine bleeding (AUB).

The joint-category analysis was exploratory. The BMI-by-HbA1c interaction was not statistically significant (P=0.271); therefore, these findings should not be interpreted as demonstrating multiplicative or biological interaction. 

HR=hazard ratio; CI=confidence interval; BMI=body mass index; HbA1c=glycated hemoglobin; AUB=abnormal uterine bleeding

Metabolic category n/events Adjusted HR (95% CI) Wald χ² P value
BMI <30 kg/m², HbA1c <8.5% 55/8 Reference - -
BMI ≥30 kg/m², HbA1c <8.5% 28/8 1.73 (0.71-4.23) 1.45 0.229
BMI <30 kg/m², HbA1c ≥8.5% 26/9 2.15 (0.91-5.10) 3.04 0.081
BMI ≥30 kg/m², HbA1c ≥8.5% 41/20 3.68 (1.65-8.23) 9.55 0.002