Table 4. Joint association of obesity and glycemic control with incident abnormal uterine bleeding (AUB).
The joint-category analysis was exploratory. The BMI-by-HbA1c interaction was not statistically significant (P=0.271); therefore, these findings should not be interpreted as demonstrating multiplicative or biological interaction.
HR=hazard ratio; CI=confidence interval; BMI=body mass index; HbA1c=glycated hemoglobin; AUB=abnormal uterine bleeding
| Metabolic category | n/events | Adjusted HR (95% CI) | Wald χ² | P value |
| BMI <30 kg/m², HbA1c <8.5% | 55/8 | Reference | - | - |
| BMI ≥30 kg/m², HbA1c <8.5% | 28/8 | 1.73 (0.71-4.23) | 1.45 | 0.229 |
| BMI <30 kg/m², HbA1c ≥8.5% | 26/9 | 2.15 (0.91-5.10) | 3.04 | 0.081 |
| BMI ≥30 kg/m², HbA1c ≥8.5% | 41/20 | 3.68 (1.65-8.23) | 9.55 | 0.002 |