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. 2026 Sep 19;18(9):e116527. doi: 10.7759/cureus.116527

Table 5. Sensitivity analyses of the principal associations with incident abnormal uterine bleeding (AUB).

HR=hazard ratio; CI=confidence interval; AUB=abnormal uterine bleeding; HbA1c=glycated hemoglobin; BMI=body mass index

Sensitivity analysis Adjusted HR (95% CI) Wald χ² P value
Excluding structural AUB
HbA1c, per 1% increase 1.43 (1.13-1.82) 8.81 0.003
BMI, per 5 kg/m² increase 1.38 (1.03-1.85) 4.60 0.032
Diabetes duration, per 5 years 1.25 (0.96-1.63) 2.72 0.099
Gynecology-documented AUB only
HbA1c, per 1% increase 1.45 (1.15-1.83) 9.55 0.002
BMI, per 5 kg/m² increase 1.39 (1.04-1.86) 4.89 0.027
Additional covariate adjustment
HbA1c, per 1% increase 1.46 (1.17-1.82) 10.83 0.001
BMI, per 5 kg/m² increase 1.40 (1.06-1.85) 5.60 0.018
Categorical exposure analysis
HbA1c ≥8.5% 2.14 (1.16-3.95) 5.92 0.015
BMI ≥30 kg/m² 1.82 (1.01-3.29) 3.95 0.047