Table 2.
Detection latency and final outbreak size in four recent filovirus disease outbreaks.
| Outbreak | Presumptive index case/spillover | Outbreak declared | Estimated detection latency | Cases reported at or near declaration | Final outbreak size and case fatality |
|---|---|---|---|---|---|
| Uganda, Sudan virus disease (2022) | Symptom onset retrospectively traced to approximately 8 August 2022 | 20 September 2022 | ~43 days (approx. 6 weeks) | Not systematically enumerated; retrospective review identified at least 43 early case-patients who had already sought care before recognition | 164 cases (142 confirmed, 22 probable); 77 deaths (case fatality ratio 47%) |
| West Africa (Guinea-origin), Ebola virus disease (2013–2016) | Index case died 28 December 2013 | WHO notified 23 March 2014 | ~85 days (approx. 12 weeks) | 49 cases, 29 deaths (case fatality ratio 59%) reported at the time of WHO notification | 28,616 cases; 11,310 deaths (case fatality ratio approx. 40%) |
| Rwanda, Marburg virus disease (2024) | Index case symptom onset retrospectively traced to approximately 8 September 2024 | 27 September 2024 | ~19 days (approx. 2.7 weeks) | Not systematically reported before declaration | 66 cases; 15 deaths (case fatality ratio 23%) |
| Democratic Republic of the Congo (Bulape), Ebola virus disease (2025) | Index case symptom onset 10 August 2025; presentation to hospital 20 August 2025 | 4 September 2025 | 25 days (approx. 3.6 weeks) | 28 suspected cases, 15 deaths (case fatality ratio 54%) reported at declaration | 64 cases (53 confirmed, 11 probable); 45 deaths (case fatality ratio 70%) |