Table 2.
Baseline clinical and paraclinical characteristics.
| Characteristics | NACa (n=68) | Non-NAC (n=60) | P value |
| Fever duration (d), mean (SD) | 4.57 (1.31) | 3.92 (1.41) | .007 |
| Right upper quadrant pain, n (%) | 29 (42.6) | 13 (21.7) | .01 |
| Nausea, n (%) | 34 (50) | 25 (41.7) | .35 |
| Vomiting, n (%) | 37 (54.4) | 19 (31.7) | .01 |
| Hemorrhage, n (%) | 28 (41.2) | 35 (58.3) | .053 |
| Mucosal bleeding, n (%) | 17 (25) | 30 (50) | .003 |
| Pleural effusion, n (%) | 33 (48.5) | 21 (35) | .12 |
| Gallbladder wall thickening, n (%) | 36 (52.9) | 24 (40) | .14 |
| Hepatomegaly, n (%) | 37 (54.4) | 12 (20) | <.001 |
| Dengue severity—grade 2, n (%) | 53 (77.9) | 54 (90) | .59 |
| Dengue severity—grade 3, n (%) | 5 (7.4) | 6 (10) | .59 |
| Hemoglobin (g/L), mean (SD) | 163.77 (15.97) | 142.55 (12.05) | .07 |
| Maximum hematocrit (L/L), mean (SD) | 0.44 (0.06) | 0.44 (0.06) | .06 |
| Minimum platelet count (G/L), median (IQR) | 12,40 (5.95-26.17) | 6.00 (2.65-12.38) | .003 |
| White blood cell count (G/L), mean (SD) | 4.95 (3.55) | 3.67 (2.30) | .55 |
| INRb, mean (SD) | 1.01 (0.08) | 1.02 (0.09) | .27 |
| ASTc (U/L), mean (SD) | 609.68 (275.10) | 511.53 (159.50) | .09 |
| ALTd (U/L), mean (SD) | 425.12 (156.13) | 419.96 (162.93) | .80 |
| Total bilirubin (μmol/L), mean (SD) | 12.45 (4.75) | 13.65 (5.24) | .19 |
aNAC: N-acetylcysteine.
bINR: international normalized ratio.
cAST: aspartate aminotransferase.
dALT: alanine aminotransferase.