Skip to main content
PMC home page
British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1990 Sep;30(3):405–409. doi: 10.1111/j.1365-2125.1990.tb03791.x

A correlation between severity of migraine and delayed gastric emptying measured by an epigastric impedance method.

R Boyle 1, P O Behan 1, J A Sutton 1
PMCID: PMC1368143  PMID: 2223419

Abstract

1. This study examined the ability of a bioimpedance method to detect the delay in gastric emptying which occurs during attacks of migraine. 2. In 64 non-migraineur control patients and 46 migraine patients outside an attack, gastric emptying rates were within the predicted normal range. 3. In contrast, rates in 14 migraineurs during 20 attacks were delayed during severe or moderate attacks and were significantly correlated with the intensity of headache, nausea and photophobia. 4. The epigastric impedance method was generally well tolerated by patients and appears to merit further investigation as a clinical method of monitoring gastric emptying of liquids.

Full text

PDF
405

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bateman D. N., Whittingham T. A. Measurement of gastric emptying by real-time ultrasound. Gut. 1982 Jun;23(6):524–527. doi: 10.1136/gut.23.6.524. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bernstein D. P. Continuous noninvasive real-time monitoring of stroke volume and cardiac output by thoracic electrical bioimpedance. Crit Care Med. 1986 Oct;14(10):898–901. doi: 10.1097/00003246-198610000-00015. [DOI] [PubMed] [Google Scholar]
  3. Dooley C. P., Reznick J. B., Valenzuela J. E. Variations in gastric and duodenal motility during gastric emptying of liquid meals in humans. Gastroenterology. 1984 Nov;87(5):1114–1119. [PubMed] [Google Scholar]
  4. Dubois A. Pathophysiology of gastric emptying: methods of measurement and clinical significance. J Clin Gastroenterol. 1979 Sep;1(3):259–266. doi: 10.1097/00004836-197909000-00014. [DOI] [PubMed] [Google Scholar]
  5. Geddes L. A., Baker L. E. The specific resistance of biological material--a compendium of data for the biomedical engineer and physiologist. Med Biol Eng. 1967 May;5(3):271–293. doi: 10.1007/BF02474537. [DOI] [PubMed] [Google Scholar]
  6. Gilbey S. G., Watkins P. J. Measurement by epigastric impedance of gastric emptying in diabetic autonomic neuropathy. Diabet Med. 1987 Mar-Apr;4(2):122–126. doi: 10.1111/j.1464-5491.1987.tb00845.x. [DOI] [PubMed] [Google Scholar]
  7. Hunt J. N., Knox M. T. The slowing of gastric emptying by four strong acids and three weak acids. J Physiol. 1972 Apr;222(1):187–208. doi: 10.1113/jphysiol.1972.sp009793. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Malagelada J. R. Gastric emptying disorders. Clinical significance and treatment. Drugs. 1982 Nov;24(5):353–359. doi: 10.2165/00003495-198224050-00001. [DOI] [PubMed] [Google Scholar]
  9. Matts S. G. Metoclopramide in the treatment of migraine. Practitioner. 1974 Jun;212(1272):887–890. [PubMed] [Google Scholar]
  10. McClelland G. R., Sutton J. A. Epigastric impedance: a non-invasive method for the assessment of gastric emptying and motility. Gut. 1985 Jun;26(6):607–614. doi: 10.1136/gut.26.6.607. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Murray P. W. Field calculations in the head of a newborn infant and their application to the interpretation of transcephalic impedance measurements. Med Biol Eng Comput. 1981 Sep;19(5):538–546. doi: 10.1007/BF02442766. [DOI] [PubMed] [Google Scholar]
  12. Sutton J. A., Thompson S., Sobnack R. Measurement of gastric emptying rates by radioactive isotope scanning and epigastric impedance. Lancet. 1985 Apr 20;1(8434):898–900. doi: 10.1016/s0140-6736(85)91674-5. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Clinical Pharmacology are provided here courtesy of British Pharmacological Society

RESOURCES