FIG. 1.

Gene arrangement of the polycistronic S1 genome segments of orthoreoviruses. The arrangement of predicted ORFs present in the ARV-176, ARV-S1133, NBV, and MRV S1 genome segments is depicted. The ORFs are shown as shaded boxes above and below a line representing the mRNA. The ORFs are identified by the name or approximate molecular mass (in kilodaltons) of the predicted gene product. Numbers indicate the first and last nucleotide numbers of each ORF (including the initiation codon, excluding the termination codon). The ARV-138 gene arrangement is identical to that depicted for ARV-176. The ARV-S1133 gene arrangement is based on the previously published sequence (46), while the MRV gene arrangement depicted is based on the published sequence of strain Dearing (12).