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. 2002 Dec;76(23):12162–12172. doi: 10.1128/JVI.76.23.12162-12172.2002

FIG. 6.

FIG. 6.

Activation of caspase-3 in HaCaT cells after FasL and TRAIL treatment with or without dexamethasone (+Dex, −Dex) induction. (A) Activation of caspase-3 in HaCaT/pMSG (upper part) and E5 cells (lower part) in the presence (+Dex) or absence (−Dex) of 1 μM dexamethasone is shown by indirect immunofluorescence with a confocal laser scanning microscope. Apoptosis was induced by the addition of either 150 ng of FasL or 500 ng of TRAIL/ml for 24 h after serum deprivation. (B) Quantitative analysis of apoptotic, uninduced (−Dex; white) or induced (+Dex; black) HaCaT/pMSG (left) and E5 (right) cells, either untreated (control) or treated for 24 h with FasL or TRAIL. Each data point is the mean value of five to six measurements of randomly chosen fields in one experiment. Exact sampling theory (Student t distribution with 4 to 5 degrees of freedom) is used for error estimation. The error bars represent the interval in which the true (population) mean is found with a probability of 95%.