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. 2002 Dec;76(23):12112–12122. doi: 10.1128/JVI.76.23.12112-12122.2002

FIG. 2.

FIG. 2.

FIG. 2.

Alignment of env gene products. (A) Alignment of predicted amino acid sequences of the ecotropic virus component of the R-MuLV complex (eco R) (28) and the ecotropic virus component of the RL-MuLV mixture (eco RL). (B) Alignment of predicted amino acid sequences of the env gene product of the MCF virus component of the R-MuLV complex (MCF R) (52) and the MCF virus component of the RL-MuLV mixture (MCF RL). Unlike the Rauscher MCF virus, the Friend MCF virus lacks aa 87 to 90 (41). The two regions with the most marked differences between xenotropic and polytropic amino acid sequences are boxed (hypervariable regions); another boxed region is the proline-rich region (40). ∗, different amino acids; -, deleted amino acids. SP, signal peptide; SU, surface protein; TM, transmembrane protein.