FIG. 3.
Enhancement of SIV transmission by ptDC-SIGN. 293T cells were transfected with either a control (pcDNA3) or ptDC-SIGN expression vector (pcDNA-ptDC-SIGN). Cells were incubated with SIVmneCL8 (A), SIVmne170 (B), or SIVmne027 (C), washed, and cultured with CEMx174 cells. Virus production was monitored by measuring p27gag antigen in the culture supernatants over a 7- to 10-day period. Results are representative of at least three independent experiments. The average p27gag antigen values ± the standard error of the mean are shown.