Table 1.
Baseline demographic and clinical characteristics of patients with recurrent aphthous stomatitis and healthy controls
|
Demographic characteristic |
RAS group (n = 35) |
Control group (n = 35) |
p-value |
|---|---|---|---|
|
Age in years, mean ± SD |
29.6 ± 6.3 |
28.2 ± 5.9 |
0.418 |
|
BMI (kg/m2) mean ± SD |
21.5 ± 2.3 |
22.2 ± 2.3 |
0.170 |
|
Sex, n (%) |
0.630 |
||
|
Male |
14 (40%) |
17 (48.6%) |
|
|
Female |
21 (60%) |
18 (51.4%) |
|
|
Smoking (current/former), n (%) |
11 (31.4%) |
6 (17.1%) |
0.012 |
|
Alcohol use, n (%) |
8 (22.9%) |
4 (11.4%) |
0.028 |
|
Systemic diseases, n (%) |
0 (0.0%) |
0 (0.0%) |
— |
|
Concomitant medication, n (%) |
0 (0.0%) |
0 (0.0%) |
— |
|
Clinical characteristics (RAU group) |
|||
|
Disease duration in years, median (IQR) |
3.8 (2.25–5.05) |
— |
— |
|
Annual recurrence episodes, median (IQR) |
6 (5.0–8.5) |
— |
— |
|
Pain VAS score (0–10), mean ± SD |
6.02 ± 1.38 |
— |
— |
|
Ulcer diameter in mm, mean ± SD |
4.45 ± 1.14 |
— |
— |
|
RAS subtype, n (%) |
— |
||
|
Minor (MiRAS) |
31 (88.5%) |
— |
|
|
Major (MjRAS) |
4 (11.5%) |
— |
|
|
Herpetiform (HU) |
0 (0.0%) |
— |
|