TABLE 1.

Naturally occurring CVB strains used in this study^a

Virus strain	Heart phenotypeb	Pancreas phenotypeb	Reference(s)
CVB3/M	Myocarditic	Pancreovirulent	67, 104, 105
CVB3/20	Myocarditic	Pancreovirulent	103
CVB3/ZU	Myocarditic	Pancreovirulent	104, 105
CVB3/AS	Myocarditic	Pancreovirulent	104, 105
CVB3/OL	Not virulent	Pancreovirulent	105
CVB3/CO	Not virulent	Pancreovirulent	104
CVB3/GA	Not virulent	Not virulent	104, 105
CVB4/Edwards	Not known	Pancreovirulent	59, 75, 94, 112
CVB4/JVB Benschoten	Not known	Not known	24

^aReferences direct the reader to data pertaining to the characterization of the phenotypes.

^b“Myocarditic” is defined as the ability to induce inflammatory lesions in mouse heart muscle within 5 to 8 days of inoculation in all or the majority of mice. “Pancreovirulent” is defined as the ability to induce inflammation of mouse pancreatic acinar tissue (pancreatitis) within 2 to 4 days of inoculation in all or many mice. “Not virulent” is defined as inducing no observable inflammatory disease or tissue destruction in any of the mice.