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. Author manuscript; available in PMC: 2026 Oct 23.
Published in final edited form as: JCO Clin Cancer Inform. 2026 Feb 5;10:e2500126. doi: 10.1200/CCI-25-00126

Table 2.

Cancer mortality rate ratios according to counties clustered by health factors included in the adapted 2025 University of Wisconsin Population Health Institute Model of Health, US (N = 3,079 counties)

Health Factor
cluster
Mortality Rate Ratios (95% Confidence Intervals)a
Z-score range N, Countiesb All Cancer Sites Lung Cancer Colorectal Cancer
1 (most healthy) −1.53 to −0.72 194 1 (ref) 1 (ref) 1 (ref)
2 −0.72 to −0.46 442 1.16 (1.13-1.19) 1.26 (1.20-1.32) 1.13 (1.09-1.18)
3 −0.46 to −0.24 448 1.23 (1.20-1.26) 1.42 (1.35-1.49) 1.22 (1.18-1.27)
4 −0.24 to −0.03 540 1.31 (1.27-1.34) 1.60 (1.53-1.67) 1.33 (1.28-1.38)
5 −0.03 to 0.18 419 1.37 (1.33-1.40) 1.71 (1.63-1.79) 1.43 (1.37-1.49)
6 0.18 to 0.40 350 1.44 (1.40-1.48) 1.90 (1.80-2.00) 1.53 (1.46-1.60)
7 0.40 to 0.64 318 1.47 (1.42-1.51) 1.96 (1.86-2.07) 1.67 (1.58-1.76)
8 0.64 to 0.91 209 1.51 (1.46-1.56) 1.99 (1.88-2.12) 1.75 (1.63-1.87)
9 0.91 to 1.25 116 1.56 (1.49-1.62) 2.10 (1.94-2.27) 1.69 (1.54-1.86)
10 (least healthy) 1.28 to 1.88 43 1.49 (1.39-1.60) 1.75 (1.51-2.02) 2.10 (1.72-2.53)
a

Data presented as age-adjusted mortality rate ratios (with 95% confidence interval. All cancer mortality rates are for the years 2018-2022.

b

Represents the total number of counties in each cluster for all cancer sites combined. The number of counties for each outcome is: all cancer – 3,079; lung cancer – 2,745; colorectal cancer – 2,180.

Abbreviation: ref, reference category