Appendix Table A2:
Cancer mortality rate ratios according to counties clustered by health factors included in the adapted 2025 University of Wisconsin Population Health Institute Model of Health by sex, US
| Health Factor Cluster |
Z-score range | N, Countiesb |
Mortality Rate Ratios (95% Confidence Intervals)a | |||
|---|---|---|---|---|---|---|
| Female population |
All Cancer Sites | Lung Cancer | Colorectal Cancer | Breast Cancer | ||
| 1 (most healthy) | −1.53 to −0.72 | 190 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| 2 | −0.72 to −0.46 | 416 | 1.13 (1.10-1.16) | 1.21 (1.14-1.27) | 1.10 (1.05-1.16) | 1.08 (1.04-1.12) |
| 3 | −0.46 to −0.24 | 428 | 1.18 (1.15-1.21) | 1.33 (1.27-1.41) | 1.17 (1.11-1.22) | 1.13 (1.09-1.17) |
| 4 | −0.24 to −0.03 | 514 | 1.24 (1.21-1.27) | 1.46 (1.38-1.53) | 1.25 (1.19-1.32) | 1.18 (1.13-1.22) |
| 5 | −0.03 to 0.18 | 408 | 1.28 (1.25-1.32) | 1.51 (1.43-1.60) | 1.31 (1.24-1.38) | 1.20 (1.15-1.25) |
| 6 | 0.18 to 0.40 | 345 | 1.32 (1.29-1.36) | 1.63 (1.53-1.72) | 1.34 (1.25-1.42) | 1.23 (1.17-1.29) |
| 7 | 0.40 to 0.64 | 307 | 1.34 (1.30-1.38) | 1.64 (1.53-1.75) | 1.49 (1.36-1.62) | 1.31 (1.22-1.39) |
| 8 | 0.64 to 0.91 | 203 | 1.37 (1.32-1.42) | 1.64 (1.52-1.78) | 1.60 (1.42-1.79) | 1.31 (1.21-1.43) |
| 9 | 0.91 to 1.25 | 112 | 1.37 (1.31-1.44) | 1.66 (1.49-1.85) | 1.31 (1.14-1.49) | 1.22 (1.10-1.35) |
| 10 (least healthy) | 1.28 to 1.88 | 38 | 1.30 (1.19-1.42) | 1.63 (1.26-2.08) | 1.78 (1.23-2.48) | 1.22 (0.90-1.60) |
| Male population | All Cancer Sites | Lung Cancer | Colorectal Cancer | Prostate Cancer | ||
| 1 (most healthy) | −1.53 to −0.72 | 191 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| 2 | −0.72 to −0.46 | 426 | 1.18 (1.14-1.21) | 1.29 (1.22-1.36) | 1.15 (1.09-1.21) | 1.13 (1.07-1.18) |
| 3 | −0.46 to −0.24 | 439 | 1.26 (1.23-1.30) | 1.48 (1.40-1.57) | 1.27 (1.21-1.33) | 1.18 (1.13-1.24) |
| 4 | −0.24 to −0.03 | 525 | 1.35 (1.32-1.39) | 1.71 (1.63-1.81) | 1.39 (1.32-1.46) | 1.19 (1.13-1.25) |
| 5 | −0.03 to 0.18 | 411 | 1.42 (1.38-1.46) | 1.85 (1.75-1.95) | 1.49 (1.42-1.57) | 1.26 (1.20-1.33) |
| 6 | 0.18 to 0.40 | 348 | 1.51 (1.47-1.56) | 2.11 (1.98-2.23) | 1.60 (1.50-1.70) | 1.25 (1.17-1.34) |
| 7 | 0.40 to 0.64 | 310 | 1.54 (1.49-1.59) | 2.21 (2.07-2.35) | 1.83 (1.70-1.97) | 1.36 (1.26-1.47) |
| 8 | 0.64 to 0.91 | 203 | 1.57 (1.51-1.64) | 2.26 (2.10-2.43) | 1.89 (1.71-2.09) | 1.45 (1.30-1.61) |
| 9 | 0.91 to 1.25 | 113 | 1.61 (1.53-1.69) | 2.34 (2.13-2.58) | 1.72 (1.51-1.95) | 1.39 (1.20-1.59) |
| 10 (least healthy) | 1.28 to 1.88 | 41 | 1.54 (1.41-1.68) | 1.97 (1.60-2.41) | 2.23 (1.62-2.97) | 1.53 (1.06-2.13) |
a
Data presented as age-adjusted mortality rate ratios (with 95% confidence interval. All cancer mortality rates are for the years 2018-2022.
b
Represents the total number of counties in each cluster. The number of counties for each outcome is: all cancer – 3,007 (males), 2,961 (females); lung cancer – 2,466 (males), 2,269 (females); colorectal cancer – 1,585 (males), 1,368 (females); breast cancer – 1,778 (females); prostate cancer – 1,612 (males).